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Romans 9:7-9

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7Nor because they are his descendants are they all Abraham’s children. On the contrary, “It is through Isaac that your offspring will be reckoned.” Gen. 21:12 8In other words, it is not the children by physical descent who are God’s children, but it is the children of the promise who are regarded as Abraham’s offspring.

9For this was how the promise was stated: “At the appointed time I will return, and Sarah will have a son.” Gen. 18:10,14