R.C. Sproul described the relationship between science, God and omniscience:

"God is a God of knowledge. He is concerned with science; indeed, He invented science. The root word of science means simply "to know." Science is the business of acquiring knowledge. ...If God is truth, then all true knowledge tells us something about God Himself... All truth is ultimately God’s truth. This means that ultimately there can be no conflict between genuine science and the truth of God." (R.C. Sproul. The Character of God. Vine Books. 1995. p. 66).

Poem: Someone once said on God’s nature:

There is nothing He does not know.

Though limitless the universe and gloriously grand,

He knows the eternal story of every grain of sand.

(MacDonald, W., & Farstad, A. (1997, c1995). Believer’s Bible Commentary : Old and New Testaments (Ps 139:1). Nashville: Thomas Nelson.)

(From a sermon by Matthew Krantz, "God is Omniscient" 7/5/08, SermonCentral.com)