Summary: There are four things in this passage that substantiate you can be assured it’s going to get better.
1. Hope 16:21
2. Joy 16:20, 22
3. Answered prayer 16:23-24
3. God’s love 16:27
4. Insight 16:13
5. Peace 16:33
IV. THE SOVEREIGN POWER OF GOD 16:33b
Believers, of all men, notwithstanding their tribulations, have reason to be of good cheer, since their sins are forgiven, the love of God is shed abroad in their hearts, their redemption draws nigh, and they have hopes of glory; and particularly, because as Christ here says, for their encouragement under all their tribulations in the world, "I have overcome the world": Satan, the god and prince of the world, with all his principalities and powers, which Christ has led captive, ransomed his people from, and delivers them from the power of; and all that is in the world, the lusts and sins of it, their damning power by the sacrifice of himself, and their governing power by his Spirit and grace; and the men of the world with all their rage and fury, whom he has trodden down in his anger, restrains by his power, and causes the remainder of their wrath to praise him; in all which conquests he makes his people share, and even makes them more than conquerors, through himself: so that they have nothing to fear from the world; nor any reason to be cast down by the tribulation they meet with in it.
Hebrews 2:14 (quickview)  Forasmuch then as the children are partakers of flesh and blood, he also himself likewise took part of the same; that through death he might destroy him that had the power of death, that is, the devil;
In 1874, a large French steamer called the Ville de Havre was on a homeward voyage from America when a collision with a sailing vessel took place. The damage to streamer was considerable, and as a result it sank quickly with loss of nearly all who had been on board. One passenger, Mrs. Horatio G. Spafford, the wife of a lawyer in Chicago, had been en route to Europe with her four children and prayed that they might be saved or, if not, that they might be willing to die, if that was God’s will. When the ship went down, the children were all lost. Mrs. Spafford was rescued by a sailor who had been rowing over the spot where the ship had sunk and found her floating in the water. Ten days later, when she reached Cardiff, she sent her husband the message: “Saved alone.” This was a great a blow, a great sadness hardly comprehensible to anyone who has not lost a child. But though a great shock, it did not destroy the peace that either of the parents, who were both Christians, had from Jesus. Thus, instead of giving vent to bitterness or defeat, Spafford wrote as a testimony of the grace of God in his experience: