Summary: There are several places in God’s Word where the need of the hour came down to just one thing. Take a look at them with me and may God bless you.
Brethren, I count not myself to have apprehended: but this one thing I do, forgetting those things which are behind, and reaching forth unto those things which are before.
Paul, the Apostle, is telling us here what one thing he intends to do. Before we examine his goals I would first like to look at some other places in God’s Word where the writer has just “one thing” upon which he wants the reader to focus.
I. One Thing Desired
One thing have I desired of the LORD, that will I seek after; that I may dwell in the house of the LORD all the days of my life, to behold the beauty of the LORD, and to inquire in his temple. (Psalms 27:4 (quickview)  KJV)
The Psalmist’s desire was to…
A. Be God’s child (dwell in the Household of God)
B. Enjoy God’s blessing (behold God’s Beauty)
C. Meditate on God’s Word (inquire about the things of God when he goes into the temple)
II. One thing lacking
Then Jesus beholding him loved him, and said unto him, One thing thou lackest: go thy way, sell whatsoever thou hast, and give to the poor, and thou shalt have treasure in heaven: and come, take up the cross, and follow me. (Mark 10:21 (quickview)  KJV)
This rich young ruler had come to Jesus wanting to know how to be saved. Jesus pointed him to the Ten Commandments. The man said He was already obeying the laws of God and had been doing so all his life. Then Jesus said, “you are lacking one thing.” He pointed out the fact that he loved his money more than God. In order to be a follower of Christ one must be willing to transfer ownership of all possessions to Jesus Christ. Everything I have must belong to Him. My time must be spent in ways that please him. My money must be used in ways that glorify God. I must not put my trust in money. Jesus said that it is easier for a camel to go through the eye of a needle than for a man who trusts in his riches to enter into Heaven. My family must be given to Christ. My abilities that God gave me must be given back to Him for His use and His glory. It matters not how religious you may be or how much money you may give to the church, if you have not given everything to God then like the rich young ruler, you still lack one thing—total commitment to Christ.
III. One thing needful
Jesus was visiting the home of his friends, Mary, Martha, and Lazarus. Martha was busy in the kitchen trying to get the meal ready. Mary was sitting at the feet of Jesus listening to His teaching. Martha was overcome with the stress of preparing the meal and complained to Jesus that Mary was not helping her. Jesus told Martha that though she was troubled by all the work that needed to be done, Mary had chosen the more important thing—setting aside time to be with Jesus. Jesus recognized that there was much work to be done, but He said, “One thing is needed and Mary is doing that one thing.” That one thing was to set aside time from the busy schedule to be with Jesus.